Heterocyclic beta-amino acids and their use as...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 333/60 (2006.01) A61K 31/00 (2006.01) A61K 31/343 (2006.01) A61K 31/357 (2006.01) A61K 31/381 (2006.01) A61K 31/405 (2006.01) A61K 31/42 (2006.01) A61K 31/428 (2006.01) A61K 31/47 (2006.01) A61P 25/00 (2006.01) A61P 25/08 (2006.01) C07D 209/08 (2006.01) C07D 215/12 (2006.01) C07D 215/14 (2006.01) C07D 215/18 (2006.01) C07D 217/14 (2006.01) C07D 261/02 (2006.01) C07D 261/08 (2006.01) C07D 277/68 (2006.01) C07D 307/78 (2006.01) C07D 307/81 (2006.01) C07D 317/60 (2006.01) C07D 319/14 (2006.01) C07D 319/18

Patent

CA 2448160

A method for preventing or treating epileptogenesis-associated diseases comprising the administration of a .beta.-heterocyclic-.beta.-aminoacid to a subject is disclosed. The disease can be for example head trauma, pain, stroke, anxiety, schizophrenia, psychosis, cerebral ischemia, Huntington's chorea, motor neuron disease, Alzheimer's disease, dementia of epilepsy.

La présente invention concerne un procédé destiné à prévenir ou à traiter les maladies associées à l'épileptogenèse, ledit procédé comprenant l'administration à une personne de .beta.-acides aminés .beta.-hétérocycliques. La maladie peut par exemple correspondre au traumatisme crânien, la douleur, l'accident vasculaire cérébral, l'anxiété, la schizophrénie, la psychose, l'ischémie cérébrale, la chorée de Huntington, la maladie des motoneurones, la maladie d'Alzheimer, la démence ou l'épilepsie.

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