Heterocyclic carboxamides

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 333/38 (2006.01) A61K 31/34 (2006.01) A61K 31/38 (2006.01) A61K 31/495 (2006.01) C07D 207/34 (2006.01) C07D 207/416 (2006.01) C07D 307/68 (2006.01) C07D 401/10 (2006.01) C07D 403/10 (2006.01) C07D 405/04 (2006.01) C07D 405/10 (2006.01) C07D 409/04 (2006.01) C07D 409/10 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2268870

Disclosed are novel compounds of the formula: <See formula I> (wherein Z is e. g., O, S, NH; X is H or substituent; R2 and R3 are H or substituent; and Y is R1-substituted phenyl, naphthyl, furyl or thiophenyl where R1 is typically cyclic amino such as substituted piperazinyl) useful in treating or preventing migraine, depression and other disorders for which a 5-HT1, agonist or antagonist is indicated.

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