Heterocyclic compound and use thereof

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 233/90 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 407/12 (2006.01) C07D 409/06 (2006.01) C07D 409/14 (2006.01) C07D 413/06 (2006.01) C07D 413/14 (2006.01) C07D 417/06 (2006.01) C07D 417/12 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01) C07D 487/08 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2728476

Compounds represented by the formulas (I) (II) wherein each symbol is as defined in the specification, and a pro-drug thereof have a superior renin inhibitory activity, and are useful as agents for the prophylaxis or treatment of hypertension, various organ damages attributable to hypertension and the like.

L'invention concerne des composés représentés par les formules (I) et (II), dans lesquelles chaque symbole est tel que défini dans la spécification, un promédicament de ces composés présentant une activité inhibitrice élevée de la rénine, lesdits composés étant utilisés comme agents pour la prophylaxie ou le traitement de l'hypertension, et de dommages organiques variés pouvant être attribués à l'hypertension et analogue.

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