Heterocyclic compounds

Details Heterocyclic compounds Heterocyclic compounds

C - Chemistry, Metallurgy

07

F

C07F 9/60 (2006.01) A61K 31/675 (2006.01)

Patent

CA 2177851

Compounds of formula (I) are NMDA antagonists and useful in the treatment and prevention of nervous sys- tem related pathological conditions resulting from overstim- ulation by excitatory amino acids. Methods for their prepa- ration and pharmaceutical compositions containing them are also comprised according to the invention.

Composés représentés par la formule (I); lesdits composés sont des antagonistes de N-méthyl-D-aspartate (NMDA) et présentent une utilité dans le traitement et dans la prévention d'états pathologiques relatifs au système nerveux et provenant d'une stimulation excessive provoquée par des acides aminés excitants. L'invention concerne également des procédés de préparation desdits composés et des compositions pharmaceutiques les contenant.

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