Heterocyclic compounds

Details Heterocyclic compounds Heterocyclic compounds

C - Chemistry, Metallurgy

07

D

260/273

C07D 513/14 (2006.01)

Patent

CA 1131226

1-22301C/79 ABTRACT OF THE DISCLOSURE A heterocyclic compound of the formula: Image or a pharmaceutically acceptable acid addition salt thereof, where- in R1 is hydrogen, lower alkyl, lower alkoxycarbonyl, formyl, nitroso, acyl phenacyl, aralkyl, a-(benzyloxycarbonyl) benzyl or a-carboxybenzyl; each of R2 and R3 is hydrogen, lower alkyl or aryl, or R2 and R3 together form a benzene ring by ring closure; and all of R4, R5 and R6 are hydrogen atoms, or both R1 and R6, and R4 and R5 together form single bonds; in which defines the term "acyl", "phenacyl", "aralkyl", "aryl" or "benzene ring" means that it may be substituted by at least one substituent at any position(s) on the aromatic nucleus, each substituent being independently selected from lower alkyl, lower alkoxy, halogen, hydroxyl, phenyl, nitro, trifluoromethyl, methylthio, methanesul- fonyl or methylenedioxy. Such compounds are useful as drugs for treating immune diseases.

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