Heterocyclic compounds

Details Heterocyclic compounds Heterocyclic compounds

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/53 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2068747

PH 36362 ABSTRACT Heterocyclic Compounds A compound of the formula I Image I wherein: A1 and A2 are each independently N or CT in which T is hydrogen or (1-4C)alkyl; R1 and R2 are each independently hydrogen, (1-6C)alkyl, or (1-4C)alkanoyl; Xl and X2 are each independently O, S or NH; and L is a (3-7C)cycloalkylene group or a (1-8C)alkylene chain optionally interrupted or extended by a group selected from phenylene, phenyleneoxy or oxyphenyleneoxy, the phenylene portion of said group being unsubstituted or substituted by one of halogen, hydroxy and (1-4C)alkoxy, provided that all heteroatoms in the group X1-L-X2 are separated from one another by at least two carbon atoms; or a pharmaceutically acceptable salt thereof, processes for preparing the compounds and pharmaceutical compositions containing them. The compounds are useful as adenosine antagonists.

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