C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 513/04 (2006.01) A61K 31/4166 (2006.01) A61K 31/429 (2006.01) A61K 31/437 (2006.01) A61K 31/4745 (2006.01) A61K 31/519 (2006.01) C07D 233/70 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01) C07D 513/20 (2006.01)
Patent
CA 2436589
The present invention relates to heterocyclic compound as cognitive enhancers. The heterocyclic compound may be represented by the formula I: (see formula I) wherein (see formula II) represents (see formula III), (see formula IV), (see formula V), (see formula VI), (see formula VII), (see formula VIII) or (see formula IX). In formula 1, R1 represents hydrogen atom, C1-C6 alkyl or benzyloxy; R2 represents methyl or nil; R3 represents hydrogen atom, C1-C6 alkyl, C2-C6 alkenyl, C3-C8 cycloalkyl or -CH2R5, wherein R5 represents thienyl or phenyl which may be substituted with C1-C6 alkyl, halogen atom or cyano; R4 represents C1-C6 alkyl, C2-C6 alkenyl, C3-C8 cycloalkyl or -CH2R6, wherein R6 represents naphthyl, thienyl or phenyl, which may be substituted with C1-C6 alkyl, halogen atom or cyano; or R3 is coupled with R4 into (see formula X), (see formula XI), (see formula XII) wherein R7 represents hydrogen atom, halogen atom, C1-C6 alkoxy, cyano or trifluoromethyl, (see formula XIII), cyclopentene or cyclopentane, provided that, when (see formula XIV) represents (see formula XV), R3 is a hydrogen atom or is coupled with R4 into (see formula XVI), (see formula XVII), (see formula XVIII) wherein R8 represents halogen atom, C1-C6 alkoxy, cyano or trifluoromethyl, (see formula XIX), cyclopentene or cyclopentane, where * is a point of attachment to formula (I).
La présente invention concerne des composés hétérocycliques représentés par la formule générale (I) dans lesquels le squelette (II) est une structure représentée par les formules (III), (IV) ou par des formules semblables. Dans ces formules R?1¿ est hydrogène, C¿1-6? alkyle ou benzyloxy, R?2¿ est méthyle ou rien, R¿3? est hydrogène, C¿1-6? alkyle, C¿1-6? alkényle, C¿3-8? cycloalkyle ou CH¿2?R¿5? [dans lequel R¿5? est phényle (qui peut être substitué par C¿1-6? alkyle, halogène ou cyano) ou thiényle], R¿4? est C¿1-6? alkyle, C¿2-6? alkényle, C¿3-8? cycloalkyle ou CH¿2?R¿6? [dans lequel R¿6? est phényle (qui peut être substitué par C¿1-6? alkyle, halogène ou cyano), naphtyle ou thiényle] ou alors, R¿3? et R¿4? peuvent être unifiés.
Fukuda Naoki
Higashi Masaya
Kawashima Seiichiro
Matsuno Toshiyuki
Saitoh Kenichi
Fetherstonhaugh & Co.
Zenyaku Kogyo Kabushiki Kaisha
LandOfFree
Heterocyclic compounds and cognitive enhancers comprising... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Heterocyclic compounds and cognitive enhancers comprising..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Heterocyclic compounds and cognitive enhancers comprising... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1981180