Heterocyclic compounds and methods of making and using thereof

Details Heterocyclic compounds and methods of making and using thereof Heterocyclic compounds and methods of making and using thereof

C - Chemistry, Metallurgy

07

D

C07D 311/12 (2006.01) A61K 31/35 (2006.01) A61K 31/425 (2006.01) A61K 31/497 (2006.01) C07D 277/34 (2006.01) C07D 487/00 (2006.01)

Patent

CA 2540460

Compounds of formula (I), and methods and/or compositions comprising compounds that are effective in modulating inflammatory responses, such as those resulting from AGE and glycated protein accumulation are provided. Methods and/or compositions comprising compounds that are effective in modulating smooth muscle cell proliferation and the diseases or conditions related thereto are also provided.

L'invention concerne des composés de formule (I) et des procédés et/ou des compositions comprenant des composés qui sont efficaces dans la modulation des réponses inflammatoires, telles que celles résultant d'une accumulation d'AGE et de protéine glycatée. L'invention concerne en outre des procédés et/ou des compositions comprenant des composés qui sont efficaces dans la modulation de la prolifération cellulaire du muscle lisse et des maladies ou états en rapport avec cette prolifération.

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