Heterocyclic compounds and their preparation and use

Details Heterocyclic compounds and their preparation and use Heterocyclic compounds and their preparation and use

C - Chemistry, Metallurgy

07

D

C07D 417/04 (2006.01) A61K 31/44 (2006.01) A61K 31/535 (2006.01) C07D 413/04 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2157580

The present invention relates to therapeutically active azabicyclic compounds of Formula (1), wherein Z1 is oxygen or sulphur, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful as stimulants of the cognitive function of the forebrain and hippocampus of mammals and especially in the treatment of Alzheimer's disease, severe painful conditions and glaucoma.

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