Heterocyclic compounds and their use for inhibiting...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 271/06 (2006.01) A61K 31/41 (2006.01) A61K 31/415 (2006.01) A61K 31/42 (2006.01) A61K 31/425 (2006.01) C07D 233/28 (2006.01) C07D 257/04 (2006.01) C07D 263/16 (2006.01) C07D 277/10 (2006.01) C07D 277/12 (2006.01)

Patent

CA 2278674

Disclosed are compounds which inhibit .beta.-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits .beta.-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

L'invention concerne des composés qui inhibent la libération du peptide bêta-amyloïde et/ou sa synthèse, et qui, par conséquent, sont utiles dans le traitement de la maladie d'Alzheimer. Elle porte aussi sur des compositions pharmaceutiques comprenant un composé qui inhibe la libération du peptide .beta.-amyloïde et/ou sa synthèse ainsi que sur des procédés pour le traitement de la maladie d'Alzheimer sur le plan prophylactique et thérapeutique à l'aide desdites compositions pharmaceutiques.

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