Heterocyclic compounds having nos inhibiting action

Details Heterocyclic compounds having nos inhibiting action Heterocyclic compounds having nos inhibiting action

C - Chemistry, Metallurgy

07

D

C07D 249/08 (2006.01) A61K 31/40 (2006.01) A61K 31/415 (2006.01) A61K 31/4196 (2006.01) C07D 207/325 (2006.01) C07D 207/335 (2006.01) C07D 231/12 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2307581

Compounds represented by general formula (I), having NOS inhibitory activities, and being useful as medicines such as a remedy for cerebrovascular disorder, wherein R1 represents aminoalkyl, etc.; R2 represents hydrogen, lower alkyl, etc.; R3 represents SR4 (wherein R4) represents lower alkyl, etc.), etc.; and Ar represents a five-membered heteroaryl group, etc.

L'invention concerne des composés représentés par la formule générale (1) présentant des activités inhibant NOS et utiles en tant que médicaments tels qu'un remède contre des troubles cérébrovasculaires, formule dans laquelle R1 représente aminoalkyle, etc.; R2 représente hydrogène, alkyle inférieur, etc.; R3 représente SR4 (où R4 représente alkyle inférieur, etc.), etc.; et Ar représente un groupe hétéroaryle à cinq éléments, etc..

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