Heterocyclic compounds, processes for their preparation and...

Details Heterocyclic compounds, processes for their preparation and... Heterocyclic compounds, processes for their preparation and...

C - Chemistry, Metallurgy

07

D

260/328.2

C07D 333/38 (2006.01)

Patent

CA 1152517

A B S T R A C T Heterocyclic compounds, processes for their preparation and their use, Thiophene carboxamides are described of general formula I Image in which the amide function is in the 2- or 3-position on the thiophene ring, Rl to R5 inclusive are hydrogen atoms or lower alkyl groups, X is -CH2-, -O- or -NR6- where R6 is hydrogen or a lower alkyl group, n is a number from O to 3 and Ar is an optionally substituted phenyl group and their physiologically acceptable salts. The compounds have been found to lower blood pressure in animals and to exhibit a blocking action at .beta.-adrenoreceptors and their use is indicated for the treatment of cardiovascular disorders such as hypertension and angina. Some of the compounds also exhibit a blocking action on .beta.-adrenoreceptors and their use is indicated for the treatment of hyper- tention. The compounds may be formùlated in conven- tional manner together with physiologically acceptable carriers or excipients.

355064

Affiliated with

Also associated with

Rating

Heterocyclic compounds, processes for their preparation and... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Heterocyclic compounds, processes for their preparation and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Heterocyclic compounds, processes for their preparation and... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-184615