Heterocyclic compounds, their production and use

Details Heterocyclic compounds, their production and use Heterocyclic compounds, their production and use

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) C07D 401/04 (2006.01) C07D 409/04 (2006.01) C07D 487/04 (2006.01) C07D 491/052 (2006.01) C07D 495/04 (2006.01) C07D 498/04 (2006.01) C07D 513/04 (2006.01)

Patent

CA 2135440

Abstract A movel compound represented by the formula: Image wherein Ring A and Ring B respectively stands for an optionally substituted homo- or hetero-cyclic ring, and at least one of them stands for an optionally substituted heterocyclic ring stand; Ring C stands for an optionally substituted benzene ring; R stands for a hydrogen atom or an optionally substituted hydrocarbon residue; one of X and Y stands for -NR1- (R1 stands for a hydrogen atom or an optionally substituted hydrocarbon residue) or -O-, and the other stands for - CO- or -CS-, or one of them stands for -N= and the other stands for =CR2- (R2 stands for a hydrogen atom, a halogen atom, an optionally substituted hydrocarbon residue, an optionally substituted amino group or an optionally substituted hydroxyl group); n denotes 1 or 2 or salts thereof which have an excellent tachykinin receptor antagonistic action and inhibitory action on plasma extravasation.

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