Heterocyclic compounds useful as dpp- iv inhibitors

Details Heterocyclic compounds useful as dpp- iv inhibitors Heterocyclic compounds useful as dpp- iv inhibitors

C - Chemistry, Metallurgy

07

D

C07D 413/04 (2006.01) A61K 31/4245 (2006.01) A61P 3/00 (2006.01) A61P 9/00 (2006.01) A61P 25/00 (2006.01) C07D 271/06 (2006.01)

Patent

CA 2576028

The invention relates to compounds of formula Z-C(R1R2)-C(R3NH2)-C(R4R5)-A (I) wherein Z, R1-R5 and A have the meaning as cited in the description and the claims as examplified by the compound (II) said compounds are useful as DPP-IV inhibitors. The invention also relates to the preparation of such compounds as well as the production and use thereof as medicament.

Cette invention concerne des composés de formule Z-C(R1R2)-C(R3NH2)-C(R4R5)-A (I), dans laquelle Z, R1-R5 et A ont la signification indiquée dans la description et les revendications, dont le composé (II) est un exemple. Lesdits composés sont utiles comme inhibiteurs de la DPP-IV. L'invention concerne également la préparation de tels composés ainsi que la production et l'utilisation de ceux-ci comme médicament.

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