Heterocyclic compounds useful as mk2 inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 471/14 (2006.01) A61K 31/437 (2006.01) A61K 31/4375 (2006.01) A61P 9/00 (2006.01) A61P 29/00 (2006.01) A61P 37/00 (2006.01) C07D 471/20 (2006.01) C07D 471/22 (2006.01) C07D 487/22 (2006.01) C07D 491/22 (2006.01)

Patent

CA 2693904

The present invention describes tetracyclic compounds of formula (IA) or (IB), wherein the symbols R, X, A, Y, R2, R3 and D are as defined in the specification, their use in the treatment of certain diseases, e.g. depending on MK-2 or TNF activity, and ways of manufacturing them.

La présente invention porte sur des composés tétracycliques de formule (IA) ou (IB), les symboles R, X, A, Y, R2, R3 et D étant tels que définis dans la description, sur l'utilisation de ces composés dans le traitement de certaines maladies, par exemple en fonction de l'activité MK-2 ou TNF, et sur des manières de les fabriquer.

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