Heterocyclic derivatives

Details Heterocyclic derivatives Heterocyclic derivatives

C - Chemistry, Metallurgy

07

K

167/222, 260/255

C07K 7/06 (2006.01) A61K 31/505 (2006.01) C07D 239/48 (2006.01) C07D 471/04 (2006.01) C07K 5/02 (2006.01) C07K 5/04 (2006.01) C07K 7/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1300807

Abstract The present invention provides a compound of formula (I): Image wherein R1 is hydrogen, C1-4 alkyl, acetyl or formyl; R2 and R3 are the same or different and are hydrogen or C1-4 alkyl; R2 is NR11R12; R11, R12, R5 and R6 are the same or different and are hydrogen, C1-4 alkyl or C1-12 acyl; R7, R8, R9 and R10 are the same or different and are hydrogen, halo, C1-4 haloalkyl, C1-4 alkyl and C1-4 alkoxy; and n is 2, 3, 4 or 5; m is o or an integer from 1 to 6; or a salt thereof, methods for the preparation of the compounds of the formula (I), intermediates in their preparations, pharmaceutical formulations containing them, and their use in the treatment of tumours.

549535

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