C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/435 (2006.01)
Patent
CA 2068946
ABSTRACT HETEROCYCLIC DERIVATIVES The invention concerns pharmaceutically useful compounds of the formula I, in which R1, R2, R3, R4, Ra, Rb, A, X and Z have the various meanings defined herein, and their non-toxic salts, and pharmaceutical compositions containing them. The novel compounds are of value in treating conditions such as hypertension and congestive heart failure. The invention further concerns processes for the manufacture of the novel compounds and the use of the compounds in medical treatment.
Gibson Keith Hopkinson
Masek Brian Bernard
Pearce Robert James
Ratcliffe Arnold Harry
Wood Robin
Smart & Biggar
Zeneca Limited
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