A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/381 (2006.01) A61K 31/41 (2006.01) A61K 31/415 (2006.01) A61P 3/04 (2006.01) C07D 231/38 (2006.01) C07D 271/10 (2006.01) C07D 277/28 (2006.01) C07D 285/00 (2006.01)
Patent
CA 2580787
Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I): where x, y, G, J, K, L, M, W, V, R2, R3, R5, R5a, R6, R6a, R7, R7a, R8 and R8a are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.
La présente invention concerne des techniques de traitement des maladies coup d'état induit par SCD chez un mammifère et de préférence chez un humain. Ces techniques consistent à administrer à un mammifère nécessitant un traitement un composé représenté par la formule (I): dans cette formule x, y, G, J, K, L, M, W, V, R2, R3, R5, R5a, R6, R6a, R7, R7a, R8 et R8a sont tels quel définis dans les spécifications. Cette invention conserve ses compositions pharmaceutiques comprenant les composés représentés par la formule (I).
Chakka Nagasree
Fu Jian-Min
Kamboj Rajender
Kodumuru Vishnumurthy
Liu Shifeng
Gowling Lafleur Henderson Llp
Xenon Pharmaceuticals Inc.
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