Heterocyclic derivatives of n-phenylamides

C - Chemistry – Metallurgy – 07 – D

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C07D 235/18 (2006.01) A61K 31/41 (2006.01) A61K 31/435 (2006.01) C07D 235/14 (2006.01) C07D 263/57 (2006.01) C07D 277/66 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2156753

New central nervous system agents conform to formula I: Image (I) wherein R = H or C1-4 alkoxy; X = CH or N; Y = NH, O or S; Z = C1-4 alkyl, C3-6 cycloalkyl, C2-3 alkenyl, NH2, C1-4 alkylamino, or C1-4 alkoxyalkyl, with the proviso that Z may not be CH3 when R=H, X=CH, and Y=NH and Z may not be CH3 when R=H, X=N and Y=NH and NHC(O)Z is in the para- position.

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