Heterocyclic derivatives which inhibit factor xa

Details Heterocyclic derivatives which inhibit factor xa Heterocyclic derivatives which inhibit factor xa

C - Chemistry, Metallurgy

07

D

C07D 405/12 (2006.01) A61K 31/395 (2006.01) A61K 31/496 (2006.01) A61K 31/50 (2006.01) A61K 31/501 (2006.01) A61K 31/506 (2006.01) A61P 7/02 (2006.01) A61P 9/00 (2006.01) A61P 9/10 (2006.01) A61P 43/00 (2006.01) C07D 401/10 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 413/12 (2006.01) C07D 471/04 (2006.01) C07D 491/04 (2006.01)

Patent

CA 2331042

The invention relates to heterocyclic derivatives of formula (I), or pharmaceutically-acceptable salts thereof, which possess antithrombotic and anticoagulant properties and are accordingly useful in methods of treatment of humans or animals. The invention also relates to processes for the preparation of the heterocyclic derivatives, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments for use in the production of an antithrombotic or anticoagulant effect.

Cette invention concerne des dérivés hétérocycliques de formule (I) ou bien leurs sels pharmaceutiquement acceptables qui possèdent des propriétés antithrombotique et anticoagulante et qui, par conséquent, sont utiles dans des procédés de traitement destiné à l'homme ou aux animaux. Cette invention concerne également des procédés de préparation des dérivés hétérocycliques, des compositions pharmaceutiques contenant ces derniers ainsi que leur utilisation dans la fabrication de médicaments destinés à produire un effet antithrombotique ou anticoagulant.

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