Heterocyclic ether substituted imidazoquinolines

Details Heterocyclic ether substituted imidazoquinolines Heterocyclic ether substituted imidazoquinolines

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) C07D 221/00 (2006.01) C07D 235/00 (2006.01) C07D 471/14 (2006.01)

Patent

CA 2431151

Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain ether and heterocyclyl or heteroaryl functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.

Cette invention concerne des composés d'imidazoquinoline et de tétrahydroimidazoquinoline présentant une fonctionnalité éther et hétérocyclile ou hétéroaryle à la position 1 qui sont utiles en tant que modificateurs de la réponse immunitaire. Les composés et compositions selon l'invention peuvent induire la biosynthèse de diverses cytokines et conviennent bien pour le traitement de diverses pathologies, dont des maladies virales et néoplasiques.

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