C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 231/14 (2006.01) A61K 31/40 (2006.01) A61K 31/404 (2006.01) A61K 31/415 (2006.01) C07D 209/34 (2006.01) C07D 209/86 (2006.01) C07D 401/06 (2006.01) C07D 403/06 (2006.01) C07D 409/06 (2006.01)
Patent
CA 2325935
The invention relates to certain indolinone-based and pyrazolylamide-based compounds, their method of synthesis, and combinatorial libraries consisting of the compounds. The invention also relates to methods of modulating the function of protein kinases using these compounds and methods of treating diseases by modulating the function of protein kinases and related signal transduction pathways.
L'invention concerne certains composés à base d'indolinone et de pyrazolylamide, leur méthode de synthèse, et des banques combinatoires constituées de ces composés. L'invention concerne également des méthodes utilisant ces composés qui permettent de moduler la fonction de protéines kinases, ainsi que des méthodes de traitement de maladies consistant à moduler la fonction des protéines kinases et les voies de transduction du signal associées.
Fong Annie
Hannah Alison
Harris Davis G.
Hirth Peter
Langecker Peter
Max-Planck-Institute For Biochemistry
Smart & Biggar
Sugen Inc.
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