C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 413/12 (2006.01) A61K 31/4439 (2006.01) A61P 35/00 (2006.01) C07D 401/12 (2006.01)
Patent
CA 2661861
The present invention relates to compounds which bind to the NR1H4 receptor (FXR) and act as agonists or partial agonists of the NR1H4 receptor (FXR). The invention further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds, and to a process for the synthesis of said compounds.
La présente invention concerne des composés qui se lient au récepteur NR1H4 (FXR) et agissent en tant qu'agonistes ou agonistes partiels du récepteur NR1H4 (FXR). L'invention concerne également l'utilisation des composés pour la préparation d'un médicament pour le traitement de maladies et/ou de troubles par liaison dudit récepteur nucléaire avec lesdits composés, et un procédé de synthèse desdits composés.
Abel Ulrich
Deuschle Ulrich
Kremoser Claus
Schulz Andreas
Phenex Pharmaceuticals Ag
Robic
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