A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/437 (2006.01) A61K 31/5383 (2006.01) A61P 25/00 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01) C07D 498/04 (2006.01) C07D 513/04 (2006.01)
Patent
CA 2555287
This invention relates to the use of compounds of formula (I) for the manufacture of a medicament useful for modulating .alpha.2 subtype GABAA receptors. The invention further relates to novel heteocyclic compounds and pharmaceutical compositions containing said compounds. In addition the invention relates to the treatment of depression, an anxiety disorder, a psychiatric disorder, a learning or cognitive disorder, a sleep disorder, a convulsive or seizure disorder or pain.
L'invention concerne l'utilisation de composés de la formule (1) dans la fabrication d'un médicament permettant de moduler les récepteurs GABA<SB>A</SB> du sous-type ?¿2?. L'invention se rapporte en outre à de nouveaux composés hétérocycliques et à des compositions pharmaceutiques contenant lesdits composés. L'invention porte également sur le traitement de la dépression, de troubles de l'anxiété, de troubles psychiatriques, de troubles de l'apprentissage ou cognitifs, de troubles du sommeil, de troubles convulsifs ou épileptiques ou de la douleur.
Loughhead David Garrett
Novakovic Sanja
O'yang Counde
Putman David George
Soth Michael
Borden Ladner Gervais Llp
F. Hoffmann-La Roche Ag
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