Heterocyclic iminobismethylenebisphosphonic acid derivatives

Details Heterocyclic iminobismethylenebisphosphonic acid derivatives Heterocyclic iminobismethylenebisphosphonic acid derivatives

C - Chemistry, Metallurgy

07

F

C07F 9/547 (2006.01) A61K 31/675 (2006.01) C07F 9/38 (2006.01) C07F 9/58 (2006.01) C07F 9/6506 (2006.01) C07F 9/6561 (2006.01)

Patent

CA 2121313

Abstract Heterocyclic iminobismethylenebisphosphonic acid derivatives The heterocyclic iminobismethylenebisphosphonic acid derivatives of the general formula (I) Image (I) wherein n is an integer of O - 5 and the group of the formula Image represents a 4 - 7 membered monocyclic or 7 - 11 membered condensed heterocyclic ring group which may be substituted by a halogen atom or a lower alkyl group and contains 1-2 nitrogen atoms their esters and salts thereof are described. The said compounds are useful as a bone resorption inhibitor, a dental calculus formation inhibitory agent or a polyvalent metal ion complex salt forming agent.

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