C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
260/308, 167/103
C07K 5/08 (2006.01) C07K 5/06 (2006.01) C07K 5/062 (2006.01)
Patent
CA 1326107
Abstract The invention provides a series of novel heterocyclic ketones of formula I (set out herein- after) and pharmaceutically acceptable base-addition salts thereof, in which the values of R4, L, A, X and Q have the meanings defined in the following specifi- cation. The compounds of formula I are inhibitors of human leukocytic elastase. The invention also pro- vides pharmaceutical compositions containing a com- pound of formula I, or a pharmaceutically acceptable base-addition salt thereof, and processes and inter- mediates for the manufacture of compounds of formula I.
566529
Edwards Philip Duke
Lewis Joseph James
Perkins Charles William
Trainor Diane Amy
Wildonger Richard Alan
Ici Americas Inc.
Marks & Clerk
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