Heterocyclic nitrogen containing polymer coated analyte...

G - Physics – 01 – N

Patent

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G01N 27/404 (2006.01) A61B 5/00 (2006.01) A61B 5/1486 (2006.01) G01N 27/327 (2006.01) G01N 27/40 (2006.01)

Patent

CA 2676241

The present invention is directed to membranes composed of heterocyclic nitrogen groups, such as vinylpyridine and to electrochemical sensors equipped with such membranes. The membranes are useful in limiting the diffusion of an analyte to a working electrode in an electrochemical sensor so that the sensor does not saturate and/or remains linearly responsive over a large range of analyte concentrations. Electrochemical sensors equipped with membranes described herein demonstrate considerable sensitivity and stability, and a large signal-to-noise ratio, in a variety of conditions.

La présente invention concerne des membranes composées de groupes azotés hétérocycliques, tels que la vinylpyridine, et des capteurs électrochimiques équipés de telles membranes. Les membranes sont utiles pour limiter la diffusion d'un analyte vers une électrode de travail dans un capteur électrochimique, de sorte que le capteur ne sature pas et/ou reste linéairement réactif sur une large gamme de concentrations en analyte. Les capteurs électrochimiques équipés des membranes décrites ici démontrent une sensibilité et une stabilité considérables, et un grand rapport signal sur bruit, dans une variété de conditions.

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