Heterocyclic pim-kinase inhibitors

Details Heterocyclic pim-kinase inhibitors Heterocyclic pim-kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/4709 (2006.01) A61K 31/517 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2735782

New compounds, compositions and methods of inhibition of Provirus Integration of Maloney Kinase (PIM kinase) activity associated with tumorigenesis in a human or animal subject are provided. In certain embodiments, the compounds and compositions are effective to inhibit the activity of at least one PIM kinase. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a serine/threonine kinase- or receptor tyrosine kinase- mediated disorder, such as cancer.

Linvention concerne de nouveaux composés, compositions et procédés destinés à inhiber lactivité de la kinase dintégration provirale de Maloney (kinase PIM) associée à la tumorigenèse chez un sujet humain ou animal. Dans certains modes de réalisation, les composés et compositions sont efficaces pour inhiber lactivité dau moins une kinase PIM. Les nouveaux composés et compositions peuvent être utilisés soit seuls soit en combinaison avec au moins un agent supplémentaire pour le traitement dun trouble médié par la sérine/thréonine kinase ou par le récepteur tyrosine kinase, tel que le cancer.

Affiliated with

Also associated with

Rating

Heterocyclic pim-kinase inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Heterocyclic pim-kinase inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Heterocyclic pim-kinase inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1837827