C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 311/58 (2006.01) A61K 31/38 (2006.01) A61P 17/00 (2006.01) C07D 215/12 (2006.01) C07D 335/06 (2006.01) C07D 409/04 (2006.01) C07D 409/12 (2006.01)
Patent
CA 2464289
The current invention provides novel heterocyclic retinoid compounds of formula (I), wherein R1 to R5, A,B,Z and n are as defined in the description and claims. The compounds of the present invention are useful for the treatment and/or prevention of diseases such as chronic obstructive pulmonary disease, cancer and dermatological disorders.
La présente invention concerne des nouveaux composés rétinoïdes hétérocycliques de formule (I), dans laquelle R?1¿ à R?5¿, A, B, Z et n sont tels que définis dans la description et les revendications. Les composés de la présente invention sont utiles pour le traitement et/ou la prévention de maladies telles que la maladie pulmonaire obstructive chronique, le cancer et les affections dermatologiques.
Klaus Michael
Lapierre Jean-Marc
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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