Heterocyclic substituted 2-acylamino-5-thiazoles, their...

C - Chemistry – Metallurgy – 07 – D

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C07D 417/12 (2006.01) A61K 31/425 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) C07D 277/40 (2006.01) C07D 417/06 (2006.01) C07D 417/14 (2006.01) C07D 495/04 (2006.01) C07D 513/04 (2006.01)

Patent

CA 2070526

- 1 - ABSTRACT Heterocyclic substituted 2-acylamino-5-thiazoles, their preparation and pharmaceutical compositions containing them. A 2-Acylaminothiazole of formula : Image (I) in which R1 is H, an alkyl or a substituted alkyl; RIV is a cycloalkyl, an aromatic group such as phenyl or a heterocyclic group which are unsubstituted or substituted; RV is a substi- tuted alkyl, a substituted carboxy sueh as an ester or an amide; or RIV and RV together represent a phenoxyalkylene group which may be substituted on the phenyl; and Z is a heterocyclic e.g. indolyl group; or a salt of compound (I). Fig. none

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