Heterocyclic-substituted quinolone inotropic agents

Details Heterocyclic-substituted quinolone inotropic agents Heterocyclic-substituted quinolone inotropic agents

C - Chemistry, Metallurgy

07

D

167/226, 260/308

C07D 233/61 (2006.01) C07D 249/08 (2006.01) C07D 257/04 (2006.01) C07D 401/04 (2006.01) C07D 521/00 (2006.01)

Patent

CA 1292234

9387-72 Abstract A quinolone inotropic agent of the formula:- Image (I) or a pharmaceutically acceptable salt thereof, wherein "Het" is an optionally substituted 5-membered monocyclic aromatic heterocyclic group containing at least one nitrogen atom in the aromatic ring and attached by a nitrogen atom of said ring to the 5-, 6-, 7- or 8-position of said quinolone; R, which i9 attached to the 5-, 6-, 7- or 8-position, is hydrogen, C1-C4 alkyl, C1-C4 alkoxy, hydroxy, CF3, halo, cyano or hydroxymethyl; and the dashed line between the 3- and 4-positions represents an optional bond.

482424

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