Heterocyclic urea and thiourea derivatives and methods of...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 417/12 (2006.01) A61K 31/4439 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2703981

The present invention relates to novel Heterocyclic Urea and Thiourea Derivatives of formula (I), compositions comprising the Heterocyclic Urea and Thiourea Derivatives, and methods for using the Heterocyclic Urea and Thiourea Derivatives for treating or preventing a proliferative disorder, an anti-proliferative disorder, inflammation, arthritis, a central nervous system disorder, a cardiovascular disease, alopecia, a neuronal disease, an ischemic injury, a viral infection, a fungal infection, or a disorder related to the activity of a protein kinase.

L'invention concerne de nouveaux dérivés d'urée et de thiourée hétérocycliques de formule (I), des compositions comprenant les dérivés d'urée et de thiourée hétérocycliques et des procédés pour utiliser les dérivés d'urée et de thiourée hétérocycliques pour traiter et prévenir un trouble prolifératif, un trouble antiprolifératif, une inflammation, l'arthrite, un trouble du système nerveux central, une maladie cardiovasculaire, l'alopécie, une maladie neuronale, une atteinte ischémique, une infection virale, une infection fongique ou un trouble associé à l'activité d'une protéine kinase.

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