Heterocyclopyrimidines, compositions and therapeutic process

C - Chemistry – Metallurgy – 07 – D

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260/242.01, 260/

C07D 487/14 (2006.01) C07D 487/04 (2006.01)

Patent

CA 1095906

Abstract of the Disclosure Imidazopyrimidiones and other diazaheterocyclopyrimidiones having an additional fused imidazole or triazole ring have utility as bronchodilaters, mediator release inhibitors, phosphodiesterase inhibitors, and peripheral vasodilators. They are orally active and useful in the prophylaxis and treatment of asthma. A preferred compound is 4-[(4-chlorophenyl)methyl]-6,7-dihydro-3H-imidazo[1,2-a]- purin-9(4H)-one.

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