Heterocyclyl-substituted ring-fused pyridines and...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/44 (2006.01) A61K 31/505 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2303280

Corticotropin releasing factor (CRF) antagonists of formula (I) and their use in treating psychiatric disorders and neurological diseases, anxiety-related disorders, post-traumatic stress disorder, supranuclear palsy and feeding disorders as well as treatment of immunological, cardiovascular or heart- related diseases and colonic hypersensitivity associated with psychopathological disturbance and stress in mammals.

L'invention porte sur des antagonistes du facteur de libération de la cortitropine (CRF), de formule (I) et leur emploi dans le traitement chez les mammifères: de troubles psychiatriques, de maladies neurologiques, de troubles liés à l'anxiété, de troubles dus au stress post-traumatique, de la paralysie supranucléaire, des troubles de la nutrition, des maladies immunologiques, cardio-vasculaires, ou cardiaques, et de l'hypersensibilité du colon liée à des dérangements psychopathologiques et au stress.

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