Heterocyclylacrylamide compounds as fabi inhibitors and...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 405/14 (2006.01) A61K 31/444 (2006.01) A61P 31/04 (2006.01) C07D 213/75 (2006.01) C07D 405/12 (2006.01) C07D 413/12 (2006.01) C07D 471/04 (2006.01) C07D 471/14 (2006.01) C07D 471/20 (2006.01) C07D 498/04 (2006.01)

Patent

CA 2632476

In part, the present invention is directed towards compounds with FabI inhibiting properties. Such compounds may also inhibit other enzymes, including those similar to FabI either structurally or functionally, for example, Fab K. Kits and compositions that include the disclosed compounds are also provided. Methods of treating a subject with a bacterial illness is also disclosed.

La présente invention concerne en partie des composés possédant des propriétés d'inhibition FabI. De tels composés peuvent aussi inhiber d'autres enzymes, dont ceux similaires à FabI soit structurellement soit fonctionnellement, par exemple, Fab K. Sont également fournis des kits et des compositions qui incluent les composés présentés. L'invention concerne aussi des procédés de traitement d'un sujet souffrant d'une infection bactérienne.

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