Heterofunctional cellular immunological reagents, vaccines...

Details Heterofunctional cellular immunological reagents, vaccines... Heterofunctional cellular immunological reagents, vaccines...

A - Human Necessities

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A61K 39/00 (2006.01) C07K 7/00 (2006.01) C07K 14/00 (2006.01) C07K 14/03 (2006.01) C07K 14/075 (2006.01) C07K 14/09 (2006.01) C07K 14/16 (2006.01) C07K 14/18 (2006.01) C07K 14/315 (2006.01) C07K 14/42 (2006.01) C07K 14/445 (2006.01) C07K 14/47 (2006.01) C07K 14/74 (2006.01) C07K 14/80 (2006.01) C07K 19/00 (2006.01) G01N 33/53 (2006.01) G01N 33/569 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1339339

The present invention relates to a heterofunctional cellular immunological reagent comprising at least two T cell specific binding ligands covalently linked together, wherein one of the T cell specific binding ligands binds to a specific class or subclass of T cells and another of the T cell specific binding ligands is an antigen associated with disease or a causative agent of disease, or epitope thereof. The present invention also relates to vaccines containing the heterofunctional cellular immunological reagents and methods for the use of the same.

602823

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