G - Physics – 01 – N
Patent
G - Physics
01
N
167/44
G01N 33/52 (2006.01) G01N 33/538 (2006.01) G01N 33/94 (2006.01)
Patent
CA 1271706
-0- HETEROGENEOUS IMMUNOASSAY UTILIZING HORIZONTAL SEPARATION IN AN ANALYTICAL ELEMENT Abstract of the Disclosure A heterogeneous, competitive binding immu- noassay is conducted with a dry analytical element. The immunoassay is useful for determining a ligand (e.g. a therapeutic drug) and includes contacting a finite area of the element spreading layer with a sample of a liquid in the presence of a labeled ligand analog and an immobilized receptor. An im- mobilized ligand-receptor complex is formed within the finite area. Simultaneously, the uncomplexed ligand migrates horizontally away from the immobil- ized complex which remains in the center of the finite area. At least five seconds after the com- pletion of the contacting, the amount of immobilized complex is measured in the center of the finite area.
499042
Danielson Susan J.
Dappen Glen M.
Frickey Paul H.
Sanford Karl J.
Sundberg Michael W.
Danielson Susan J.
Dappen Glen M.
Eastman Kodak Company
Frickey Paul H.
Gowling Lafleur Henderson Llp
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