Heteromonocyclic compound and use thereof

Details Heteromonocyclic compound and use thereof Heteromonocyclic compound and use thereof

C - Chemistry, Metallurgy

07

D

C07D 413/10 (2006.01) A61K 31/4245 (2006.01) A61P 3/00 (2006.01) A61P 9/00 (2006.01) A61P 25/00 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2670404

A compound represented by the formula (I): wherein R1 is an oxo group, =N-R or the like; a group represented by the formula: is a group represented by the formula:;R2 is a group represented by the formula: or a salt thereof. The compound of the present invention is useful as a drug for the prophylaxis or treatment of circulatory diseases, metabolic diseases and/or central nervous system diseases.

L'invention porte sur un composé de formule (I): où R1 est un groupe oxo, =N-R ou analogue ou un groupe de formule (I); R2 est un groupe de formule (I); R3 et R4 sont chacun H, ou C1-C6 alkyle, C3-C6 cycloalkyle, C1-C6 alkoxy, C1-C6 alkylamino, Di (C1-C6) alkylamino ou C1-C6 alkylthio, tous facultativement substitués; et R5 est H, ou C1-C6 alkyle, C2-C6 alcényle, un groupe cyclique, tous facultativement substitué, -CO-R8 ou -O-R8', ou un de leurs sels. Ledit composé s'avère utile comme médicament pour la prophylaxie ou le traitement de maladies circulatoires, de troubles du métabolisme et/ou de maladies du SNC.

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