Heteropolycyclic compounds and their use as metabotropic...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 413/04 (2006.01) A61K 31/44 (2006.01) A61P 25/18 (2006.01) C07D 213/55 (2006.01) C07D 213/75 (2006.01) C07D 213/78 (2006.01) C07D 213/79 (2006.01) C07D 401/04 (2006.01) C07D 405/04 (2006.01) C07D 405/10 (2006.01) C07D 405/14 (2006.01) C07D 413/10 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/04 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2438991

The present invention provides compounds and pharmaceutical compositions that act as antagonists at metabotropic glutamate receptors, and that are useful for treating neurological diseases and disorders. Method of preparing the compounds also are disclosed.

La présente invention concerne des composés et des compositions pharmaceutiques qui agissent comme des antagonistes au niveau des récepteurs métabotropiques du glutamate, et qui sont utiles pour le traitement de maladies et de troubles neurologiques. La présente invention concerne également des procédés de fabrication de ces composés.

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