Heterosubstituted pyridine derivatives as pde 4 inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 213/89 (2006.01) A61K 31/4427 (2006.01) A61P 11/00 (2006.01) C07D 213/74 (2006.01) C07D 213/76 (2006.01) C07D 213/79 (2006.01) C07D 401/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2369323

The invention encompasses the novel compound of Formula (I) useful in the treatment of diseases, including asthma, by raising the level of cyclic adenosine-3',5'-monophosphate (cAMP) through the inhibition of phosphodiesterase IV (PDE 4) or a pharmaceutically acceptable salt or hydrate thereof. The invention also encompasses pharmaceutical compositions and methods for treatment.

L'invention concerne un nouveau composé de formule (I) utilisé dans le traitement de maladies, telles que l'asthme, pour élever le niveau d'adénosine-3',5'-monophosphate cyclique (cAMP) par inhibition de la phosphodiestérase IV (PDE 4). L'invention concerne également un sel ou un hydrate pharmaceutiquement acceptable de ce composé, ainsi que des compositions pharmaceutiques et des procédés de traitement.

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