Hexacyclic compounds

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 491/22 (2006.01) A61K 31/47 (2006.01) C07D 209/00 (2006.01) C07D 221/00 (2006.01) C07D 239/00 (2006.01) C07D 311/00 (2006.01)

Patent

CA 2468824

The present invention relates to hexacyclic compound of the formula [1], wherein Z, R1, R2, R3 and R4 are as defined in the description and claims and pharmaceutically acceptable salts thereof. These compounds are useful in the treatment of cell proliferative disorders.

Composé hexacyclique de formule [1] dans laquelle Z, R?1¿, R?2¿, R?3¿ et R?4¿ sont tels que définis dans le descriptif et les revendications et sels acceptables sur le plan pharmaceutique dudit composé. Ces composés sont utiles pour traiter les troubles liés à la prolifération cellulaire.

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