Hexafluoroisopropanol substituted ether derivatives

Details Hexafluoroisopropanol substituted ether derivatives Hexafluoroisopropanol substituted ether derivatives

C - Chemistry, Metallurgy

07

C

C07C 69/92 (2006.01) A61K 31/085 (2006.01) A61K 31/192 (2006.01) A61K 31/216 (2006.01) A61K 31/235 (2006.01) A61K 31/421 (2006.01) A61K 31/423 (2006.01) A61K 31/428 (2006.01) C07C 43/23 (2006.01) C07C 59/68 (2006.01) C07C 65/24 (2006.01) C07C 69/734 (2006.01) C07D 261/20 (2006.01) C07D 263/32 (2006.01) C07D 275/04 (2006.01)

Patent

CA 2581945

The invention is concerned with hexafluoroisopropanol substituted ether derivatives of formula (I), wherein Rl to R3 are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds bind to LXR alpha and LXR beta and can be used as medicaments.

L'invention concerne des dérivés d'éther substitués par du hexafluoroisopropanol de formule (I), dans laquelle R1 à R3 ont la signification indiquée dans la description et les revendications, ainsi que des sels et des esters acceptables sur le plan pharmaceutique de ceux-ci. Lesdits composés se lient au LXR alpha et au LXR bêta et peuvent être utilisés en tant que médicaments.

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