C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/209, 260/238
C07D 498/06 (2006.01) A61K 31/55 (2006.01) C07D 219/10 (2006.01) C07D 221/16 (2006.01) C07D 513/06 (2006.01)
Patent
CA 2030715
The present invention relates to hexahydro-1H-quino [4,3,2-ef] [1,4] benzoxazepines and related compounds of formula 1, Image and a process for their preparation and intermediates thereof. The compounds of the invention are able to relieve memory dysfunction, particularly dysfunctions associated with decreased cholinergic activity such as those found in Alzheimer's disease and can, therefore, be used as medicaments.
Kapples Kevin James
Shutske Gregory Michael
Tomer John Dick IV
Aventis Pharmaceuticals Inc.
Bereskin & Parr
Hoechst-Roussel Pharmaceuticals Inc.
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