C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/435 (2006.01) A61P 25/00 (2006.01)
Patent
CA 2612495
Hexahydro-pyrroio-isoquinoline compounds of formulas I, II, III are histamine H3 receptor and serotonin transporter modulators useful in the treatment of histamine H3 receptor- and serotonin-mediated diseases such as depression and related diseases.
L'invention concerne des composés d'hexahydro-pyrrolo-isoquinoline représentés par les formules I, II, III, qui sont des modulateurs du récepteur de l'histamine H3 et du transporteur de la sérotonine, convenant pour le traitement des maladies médiées par le récepteur de l'histamine H3 et par la sérotonine, telles que la dépression et les maladies analogues.
Apodaca Richard
Barbier Ann J.
Carruthers Nicholas I.
Gomez Leslie A.
Keith John M.
Janssen Pharmaceutica N.v.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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