C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 17/06 (2006.01) A61K 31/215 (2006.01) A61K 31/365 (2006.01) C07C 69/30 (2006.01) C07C 69/52 (2006.01) C07C 69/675 (2006.01) C07C 309/63 (2006.01) C07D 309/30 (2006.01) C07D 407/12 (2006.01) C07D 409/12 (2006.01) C07F 7/18 (2006.01) C12N 9/02 (2006.01) C12P 7/62 (2006.01)
Patent
CA 2112442
ABSTRACT OF THE DISCLOSURE Compounds of formula (I): Image (I) [wherein R1 represents a group of formula (II) or (III): Image (II) (III) R2 is alkyl, alkenyl or alkynyl; R3 and R4 are each hydrogen, alkyl, alkenyl or alkynyl; R5 is hydrogen or a carboxy-protecting group; Ra is hydrogen or a group of formula and -OR6; R6, R6a and R6b are each hydrogen, a hydroxy-protecting group, alkyl, alkanesulfonyl, halogenated alkanesulfonyl or arylsulfonyl] and their salts and esters have the ability to inhibit the synthesis of cholesterol, and can thus be used for the treatment and prophylaxis of hypercholesterolemia and of various cardiac disorders.
Hamano Kiyoshi
Ishihara Sadao
Kitazawa Eiichi
Koga Teiichiro
Kogen Hiroshi
Marks & Clerk
Sankyo Company Limited
LandOfFree
Hexahydroaphthalene ester derivatives, their preparation and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Hexahydroaphthalene ester derivatives, their preparation and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hexahydroaphthalene ester derivatives, their preparation and... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1630127