Hexahydroazepine derivatives, a process for their...

Details Hexahydroazepine derivatives, a process for their... Hexahydroazepine derivatives, a process for their...

C - Chemistry, Metallurgy

07

D

C07D 223/04 (2006.01) A61K 31/55 (2006.01) C07D 295/067 (2006.01) C07D 295/073 (2006.01) C07D 295/084 (2006.01) C07D 295/088 (2006.01) C07D 295/108 (2006.01)

Patent

CA 2044484

The present invention relates to hexahydroazepine derivatives of formula (See figure 1) in which: A = -CO-CH2-, -CH(OH)-CH2-; -CH2-CH2-; -CH=CH-; -C=C-; x = H or a halogen; Y = cyclohexyl or, when X is H, phenyl. It likewise relates to the salts of the said derivatives, to a process for the preparation of these and to the pharmaceutical compositions containing them, more particularly as antipsychotic agents.

La présente invention concerne des dérivés d'hexahydroazépine de formule (voir figure 1) dans lesquels : A = -CO-CH2-, -CH(OH)-CH2-; -CH2-CH2-; -CH=CH-; -C=C-; x = H ou un halogène; Y = cyclohexyle ou, lorsque X est H, un phényle. Elle concerne également les sels desdits dérivés, un procédé pour leur préparation et les compositions pharmaceutiques les contenant, plus particulièrement à titre d'agents antipsychotiques.

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