Hexahydroazepine piperidine and pyrrolidine derivatives

Details Hexahydroazepine piperidine and pyrrolidine derivatives Hexahydroazepine piperidine and pyrrolidine derivatives

C - Chemistry, Metallurgy

07

D

260/324, 260/241

C07D 207/267 (2006.01) C07D 207/08 (2006.01) C07D 207/26 (2006.01) C07D 211/22 (2006.01) C07D 211/76 (2006.01) C07D 223/04 (2006.01) C07D 223/10 (2006.01)

Patent

CA 1113092

Abstract The invention concerns novel 2-oxo-hexahydro- azepine, - piperidine and -pyrrolidins of formula (1) Image (I) where n is 2, 3 or 4, R1 is hydrogen, lower alkyl or aryl(lower)alkyl and R1 is lower alkyl. The compounds may be aromatised and the aromatised compounds converted to 3,3-disubstituted-haxahydroazepine, -piperidine and -pyrrolidine compounds having pharmacological activity, particularly analgesic activity.

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