Hexahydroazepino (4, 5-g) indoles and indolines as 5-ht...

Details Hexahydroazepino (4, 5-g) indoles and indolines as 5-ht... Hexahydroazepino (4, 5-g) indoles and indolines as 5-ht...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/55 (2006.01) A61P 25/00 (2006.01) A61P 25/18 (2006.01) A61P 25/22 (2006.01)

Patent

CA 2452610

The present invention provides compounds of Formula (I): wherein R1, R2, R3, R4, R5, R6 and --- have any of the values defined in the specification, as well as pharmaceutical compositions comprising the compounds. The invention also provides therapeutic methods as well as processes and intermediates useful for preparing compounds of Formula (I). The compounds are useful as 5- HT ligands.

L'invention porte sur des composés de formule (I) dans laquelle: R?1¿, R?2¿, R?3¿, R?4¿, R?5¿, R?6¿ et --- peuvent prendre toute valeur définie dans la spécification, et sur des préparations pharmaceutiques comprenant lesdits composés. L'invention porte également des méthodes thérapeutiques et sur des procédés et intermédiaires utilisée pour la préparation desdits composés qui s'avèrent utiles comme ligands du récepteur 5-HT.

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