C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 231/54 (2006.01) A61K 31/416 (2006.01) A61K 31/4439 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2716136
The present invention is directed to hexahydrocyclopentyl.function.]indazole carboxamides and derivatives thereof as selective glucocorticoid receptor ligands useful for treating a variety of autoimmune and inflammatory diseases or conditions. Pharmaceutical compositions and methods of use are also included.
La présente invention concerne des carboxamides dhexahydrocyclopentyl[f]indazole et des dérivés de ceux-ci servant de ligands de récepteurs de glucocorticoïde sélectifs, utiles pour traiter une variété de maladies ou d'affections inflammatoires et auto-immunes. La présente invention concerne également des compositions pharmaceutiques et des procédés pour leur utilisation.
Dankulich William P.
Kaufman Mildred L.
Mcmaster Danielle M.
Meissner Robert S.
Mitchell Helen J.
Gowling Lafleur Henderson Llp
Merck Sharp & Dohme Corp
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