C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
260/369.4, 260/4
C07C 69/34 (2006.01) C07D 303/16 (2006.01) C07D 303/40 (2006.01)
Patent
CA 1192210
ABSTRACT OF THE DISCLOSURE The invention relates to new hexitols having the general formulae (I) and (II), Image (I) Image (II) wherein the hexitol skeleton is dulcitol, mannitol or iditol, X represents halogen, preferably bromine, R is a saturated or unsaturated C4-10 alkylcarbonyl group which also contains a free carboxy group, and R1 is hydrogen, a saturated or unsaturated C4-10 alkyl- carbonyl group which also contains a free carboxy group, a satur- ated or unsaturated C2-10 alkylcarbonyl group, a saturated or unsaturated C4-10 alkylcarbonyl group which also contains an alkoxycarbonyl group, or a saturated or unsaturated C8-10 aralkyl- carbonyl group, and salts of these compounds. The new compounds according to the invention have tumour-inhibiting effects. The above compounds are prepared according to the inven- tion so that a) a compound of the general formula (IX), wherein the hexitol skeleton is dulcitol, mannitol or iditol, Q is a saturated or unsaturated C11-17 alkylcarbonyl group which also contains a benzyloxycarbonyl group, and
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Di Gleria Katalin
Eckhardt Sandor
Elekes Ilona
Hindy Ivan
Institoris Laszlo
Chinoin Gyogyszer - Es Vegyeszeti Termekek Gyara Rt.
Fetherstonhaugh & Co.
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